Deamidated gliadin peptide ELISA

Detection of gliadin antibodies has been used for a long time in celiac disease diagnostics, but suffered from a low specificity.
This disadvantage was overcome by the introduction of deamidated gliadin peptides as antigen. The ratio behind is that tissue transglutaminase catalyzes gliadin deamidation in the intestinal mucosa of celiac disease patients, resulting in deamidated gliadin peptides which are recognized by HLA receptors of immune cells. Therefore deamidated gliadin antibodies are specific for celiac disease.

Our ELISAs for detection of deamidated gliadin antibodies (E019/E020) use DGPx1 as antigen.
DGPx1 (G007) is our novel deamidated gliadin peptide, fused to a carrier protein and produced by recombinant techniques intended for usage as antigen in deamidated gliadin antibody detection.

Deamidated gliadin peptide DGPx1
- recombinantly produced and highly purified
- efficient coating under standard conditions
- high diagnostic specificity
- license free

ELISA with deamindated gliadin peptide antigen  

DGPx1-fusion protein allows efficient coating
and accessibility to the antigen.


Art. No.
Name
Quantity
Price
E019 ZediXclusive DGPx1-ab ELISA (IgA)
ELISA for the determination of autoantibodies (IgA) against deamidated gliadin peptide
1 Kit
520 €
E020 ZediXclusive DGPx1-ab ELISA (IgG)
ELISA for the determination of autoantibodies (IgG) against deamidated gliadin peptide
1 Kit
520 €

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    • Transglutaminases in Medicine

      03.08.2017 - 05.08.2017
      Debrecen, Hungary

    • 15th Congress on Amino Acids, Peptides and Proteins

      07.08.2017 - 11.08.2017
      Vienna, Austria

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      08.09.2017 - 10.09.2017
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      13.11.2017 - 16.11.2017
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    • Gordon Research Conference on: Transglutaminases in Human Disease Processes

      16.06.2018 - 17.06.2018
      Les Diablerets, Switzerland