Recombinant Gliadin Peptides

Gliadin peptides derived from Triticum aestivum (wheat) are the main immunotoxic antigens in celiac disease. They are a substrates for tissue transglutaminase, which specifically deamidates glutamine residues within these peptides, and therefore strongly increases their immunogenicity (Dørum S. et al., J. Proteome Res. 2009; 8:1748-55).

We offer a set of fusion proteins that carry the different native and deamidated peptide sequences that facilitate the analysis of antibodies found in celiac disease related samples. See also section: Celiac Disease Products

gliadin peptides and DGP variants

Art. No.
Name
Quantity
Price
G051 26mer gliadin peptide
(26mer-gamma gliadin peptide (aa 59-84) fused to carrier protein)
250 µg
370 €
G052 33mer gliadin peptide
(33mer-alpha gliadin peptide (aa 57-89) fused to carrier protein)
250 µg
370 €
G053 26mer DGP
(26mer-deamidated gamma gliadin peptide (aa 59-84) fused to carrier protein)
250 µg
370 €
G054 33mer DGP
(33mer-deamidated alpha gliadin peptide (aa 57-89) fused to carrier protein)
250 µg
370 €
G055 Carrier protein control
(Control for G051, G052, G053 and G054)
250 µg
370 €
G056 DGP and Gliadin peptides (Set No 1)
(G051, G052, G053, G054 and G055, 100 µg each)
1 Set
740 €

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    • Press release: Dr. Falk Pharma and Zedira announce completion of phase 1b clinical trial of ZED1227 for the treatment of celiac disease and move on to proof of concept study
    • Pressemitteilung: Dr. Falk Pharma und Zedira geben den Abschluss der Phase 1b-Studie für ZED1227 zur Zöliakie-Therapie bekannt und planen Start der Wirksamkeitsstudie
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  • Events  

    • Transglutaminases in Medicine

      03.08.2017 - 05.08.2017
      Debrecen, Hungary

    • 15th Congress on Amino Acids, Peptides and Proteins

      07.08.2017 - 11.08.2017
      Vienna, Austria

    • 17th International Celiac Disease Symposium

      08.09.2017 - 10.09.2017
      New Delhi, India

    • NLSDays 2017

      12.09.2017 - 14.09.2017
      Malmö, Sweden

    • BIO-Europe

      06.11.2017 - 08.11.2017
      Berlin, Germany

    • MEDICA

      13.11.2017 - 16.11.2017
      Düsseldorf, Germany

    • Gordon Research Conference on: Transglutaminases in Human Disease Processes

      16.06.2018 - 17.06.2018
      Les Diablerets, Switzerland