Transglutaminase 2

Polyclonal antibody to human tissue transglutaminase (TG2)

Quantity Unit Price Status
500 µg 400 € Available
Documents
Art. No.
A014
Host
Rabbit
Immunogen
Human tissue transglutaminase (full length protein with N-terminal hexahistidin-tag) recombinantly produced in insect cells
Specificity
Specificity of A014 was determined with human transglutaminases (TG1 – TG7, FXIII) and TG2 of different species.
A014 has no cross reactivity to TG1, TG6 and TG7 and very slight cross reactivity to TG3, TG4, TG5 and FXIII.
A014 also recognizes TG2 form various species, although at a lower signal intetnsity. Note: A014 also detects dog TG2.

The epitopes the polyclonal antibody to human TG2 binds to were determined using PEPperCHIP® Transglutaminase Microarray (P111).
A014 recognizes the epitopes Y149LDSE153, D242NNYGDGVSP251, N318EFGEIQG325, Q348PGYEG353, Q355ALDPTPQEK364, D438ITHT442, P446EGSSEEREAFT457, F492AHITNNTAEE502, L629TEEQ633, E637IPDPVEAG645

For more information klick here:
Poster presentation at GRC, 2016 (Girona, Spain)
Formulation
The antibody is lyophilized from 200 μL 0.02 M Tris-HCl buffer pH 8.0, 0.028 M NaCl, 2 mg/mL human serum albumin, azide free.
Application
Western-Blotting, immuno-fluorescence, immuno-histochemistry Note: For FACS antibody A028 (FITC-labeled A014) is recommended.
Storage
Stable for a minimum of 2 years at –20°C as lyophilized powder
Delivery is possible at ambient temperature
Reference(s)
Dulay et al., Biosens. Bioelectron. 2011, 26:3852-6
Note
Intended for research use only, not for use in human, therapeutic or diagnostic applications.

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