FXIII-Inhibitors

Tridegin

(rec. produced in E. coli, gene derived from Haementeria ghilianii)
Quantity Unit Price Status
200 µg 510 € Available
Documents
Art. No.
T087
Synonym
His6-Tridegin
Background info
Tridegin is a potent and highly specific inhibitor of human blood coagulation factor XIIIa that has been isolated from Haementeria ghilianii (Finney et al.,1997).
T087 is a recombinant variant of Tridegin containing a carboxyterminal hexahistidine-tag.
Molecular Weight
7.5 kDa
Source
Recombinantly produced in E. coli
Purity
> 95% [by SDS-PAGE]
Appearance
White lyophilized solid
Reagents
Recombinant Tridegin is lyophilized from 20 mM Tris-HCl pH 8.0, 50 mM NaCl, 1 mM EDTA, 10 mg/ml sucrose
Reconstitution
Add the volume of H2O the protein is lyophilized from (see Certificate of Analysis) to the vial of lyophilized powder. Rotate vial gently until solid dissolves. After reconstitution the solution should be stored frozen in working aliquots. Keep cooled on ice for short term storage.
Storage
Storage for several months is possible at ≤ - 20°C.
Delivery is possible at ambient temperature
Reference(s)
Böhm et al., J. Med. Chem. 2014, 57:10355-65
Finney et al., Biochem. J. 1997, 324:797-805
Wallis et al., Blood Coagul. Fibrinolysis. 1997, 8:291-5
Seale et al., Thromb. Haemost. 1997, 77:959-63
Note
Intended for research use only, not for use in human, therapeutic or diagnostic applications.

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