2-[(2-oxopropyl)thio] imidazolium derivates

1,3-Dimethyl-2-[(2-oxopropyl)thio]imidazolium chloride



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Art. No. D003
Synonym NTU283
Molecular Formula C8H13ClN2OS
Molecular Weight 220.72
Purity by HPLC >95 % (HPLC)
Appearance white solid
Solubility Dissolve e.g. 3.65 mg in 330.7 μl PBS buffer to obtain a 50 mM solution
Application Inhibitor for transglutaminase
D003 is a weak blocker of tissue transglutaminase with an IC50 of about 1.0 μM
Storage Store at -20°C, desiccate
Reference(s) Freund, K. et al. Biochemistry 1994, 33, 10109.
Skill, N.. et al. J. Biol. Chem. 2004, 279, 47754.
Hugues L.-J. et al. J. Biol. Chem. 2012, 287, 18005.
Sánchez-Lara A. et al. Vet Pathol. 2015, 52, 513.
Note Intended for research use only, not for use in human, therapeutic or diagnostic applications.

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