LDN-27219

LDN 27219



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10 mg 385 € available


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Art. No. D016
Synonym CAS 312946-37-5
Molecular Formula C20H16N4O2S2
Molecular Weight 408.50
Purity by HPLC >95 % (214 nm)
Appearance White solid
Solubility 10 μM in 0.1% (v/v) DMSO / aqueous buffers.
Pre-dissolve e.g. 10 mg in 245 μl DMSO (100 mM).
Take e.g. 10 μl of the 100 mM stock solution and add 90 μl DMSO to obtain a 10 mM stock solution - dilute by adding 9990 μl buffer or assay components to obtain your final assay solution (10 μM).
DMSO stock solutions are sterile and can be stored at -20°C for at least 6 months. To avoid too many freeze-thaw cycles, we strongly recommend storage of aliquots.
Application Reversible, slow-binding Transglutaminase 2 (TG2) inhibitor (IC50 = 0.25 μM), binding at the enzyme’s GTP site.[2]
Storage Store at -20°C, desiccate
Reference(s) [1] E. Duval et al. Bioorg. Med. Chem. Lett. 2005, 15, 1885-1889.
[2] A. Case, R.L. Stein Biochemistry 2007, 46, 1106-1115.
Note INTENDED FOR RESEARCH USE ONLY, NOT FOR USE IN HUMAN, THERAPEUTIC OR DIAGNOSTIC APPLICATIONS.

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