Proteases

Thrombin-Generation-Assay Substance, fluorescent

Quantity Unit Price Status
25 mg 200 € Available
Documents
Art. No.
Z020
Synonym
Z-Gly-Gly-Arg-AMC
Molecular Formula
C30H34F3N7O9 (free base: C28H33N7O7)
Molecular Weight
693.63 (free base: 579.60)
Purity by HPLC
>95 % (214 nm)
Appearance
Pale yellow solid
Solubility
50 μM in 0.1% (v/v) DMSO / aqueous buffers
Application
“Slow” acting thrombin substrate for the determination of thrombin generation in plasma
Also suitable for urokinase, trypsin, and tissue-type plasminogen
Storage
Store at -20°C, desiccate
Reference(s)
Kintigh J. et al. Res. Pract. Thromb. Haemost. 2017, 2, 42-48.
Devreese K. et al. Thromb. Haemost. 2007, 98, 600-613.
Hemker H.C. et al. Pathophysiol. Haemost. Thromb. 2002, 32, 249-253.
Zimmerman M. et al. PNAS 1978, 75, 750-753.
Note
INTENDED FOR RESEARCH USE ONLY, NOT FOR USE IN HUMAN, THERAPEUTIC OR DIAGNOSTIC APPLICATIONS.

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