Transglutaminase 2

Biotinylated human Open tTG™

(biotinylated inhibited human tissue transglutaminase (T051), stabilized in its open conformation, recombinantly produced in insect cells)
Quantity Unit Price Status
50 µg 400 € Available
250 µg 1600 € Available
Documents
Art. No.
T148
Synonym
Tissue-type Transglutaminase, TG2, TGase 2, proteinglutamine-γ-glutamyltransferase
Molecular Weight
79 kDa (Val224-allele, Kanchan et al., Biochem. J. 2013, 455:261–72)
Source
Recombinant produced in insect cells
Purity
> 95% (visually by SDS-PAGE)
Appearance
Liquid
Reagents
The Transglutaminase is formulated in 10 mM Sodium Phosphate pH 8.0, 15 mM NaCl. Sample contains 50% glycerol.
Application
Open tTGTM may be used for immunoprecipitation and detection of autoantibodies in body fluid samples from patients suffering from autoimmune diseases like psoriasis or gluten sensitive enteropathy. For coating of micro titer plates the addition of 10 mM Ca2+ is recommended.
Storage
Store working aliquots at ≤ - 20°C. Avoid repeated freezing and thawing.
Note
INTENDED FOR RESEARCH USE ONLY, NOT FOR USE IN HUMAN, THERAPEUTIC OR DIAGNOSTIC APPLICATIONS

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