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Microarrays

The PEPperCHIP® Transglutaminase Microarray is based on 6 transglutaminase variants (hFXIII, hTG1, hTG2, hTG3, hTG4 and hTG6) and can be used for

  • high resolution epitope mapping of anti-transglutaminase antibodies
  • antibody specificity analysis with 6 different transglutaminase antigens
  • serum antibody screening for anti-transglutaminase antibodies
  • isotype-specific IgG and IgA profiling from serum and plasma
  • correlation of anti-transglutaminase antibody responses with pathogenesis

The standard slide format of PEPperCHIP® Transglutaminase Microarrays facilitates application with standard lab infrastructures and most microarray scanners. Additional PEPperCHIP® Accessories support the straightforward use of the state-of-the-art peptide microarray solutions to ensure optimized assay conditions and best data quality.

Read more about PEPperCHIP Epitope Mapping
Poster presentation at GRC, 2016 (Girona, Spain)

Products

  • Zedira offers a huge portfolio of reliable specialist transglutaminase related products meant to catalyze research and development, both in academia and industry.
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News  

  • imagePress release: Zedira announces ISO 9001:2015 certification
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  • imageZedira communication: Joint poster presentation on “Feasibility of a new automated FXIII activity assay”
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  • imageArtikel in DZG Aktuell 01/2019 über die klinische Wirksamkeitsstudie unseres potentiellen Zöliakie Medikaments (deutsch)
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  • imagePreview: Catalogue Editorial 2019
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  • Press release: Dr. Falk Pharma and Zedira announce start of the phase 2a proof of concept study of ZED1227 for the treatment of celiac disease
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  • Artikel in DLG-Lebensmittel – 06/2017 zur Bestimmung von Transglutaminase in Lebensmitteln (deutsch)
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  • Zedira publication: Microbial Transglutaminase Used in Bread Preparation at Standard Bakery Concentrations Does Not Increase Immunodetectable Amounts of Deamidated Gliadin
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  • Pressemitteilung: Dr. Falk Pharma und Zedira geben den Abschluss der Phase 1b-Studie für ZED1227 zur Zöliakie-Therapie bekannt und planen Start der Wirksamkeitsstudie
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  • Press release: Dr. Falk Pharma and Zedira announce completion of phase 1b clinical trial of ZED1227 for the treatment of celiac disease and move on to proof of concept study
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  • Press Release: Dr. Falk Pharma GmbH and Zedira enter a phase 1b clinical trial for a celiac disease drug
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  • Zedira publication: Microbial transglutaminase has a lower deamidation preference than human tissue transglutaminase on a celiac disease relevant wheat gliadin T-cell epitope
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  • Press release: Additional subsidy funding for clinical development of a celiac disease drug
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  • Pressemitteilung: Zusätzliche Fördermittel für die klinische Entwicklung eines Zöliakie-Medikamentes
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  • Press Release: Cooperation between Zedira and Cardiff University - Transglutaminase 6 is the focus of new research into ataxia
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  • Press Release: Dr. Falk Pharma and Zedira enter phase I clinical trials for a celiac disease drug
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  • Press release: Zedira receives further funding to develop Factor XIIIa-blockers for safe anticoagulation
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Events  

  • New Frontiers Symposium

    23.11.2019
    Chicago, USA

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  • World ADC London 2020

    02.03.2020 - 05.03.2020
    London, Great Britain

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  • Celiac Disease Center's International Symposium

    06.03.2020 - 07.03.2020
    New York, USA

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  • Gordon Research Conference - Transglutaminases in Human Disease Processes

    14.06.2020 - 19.06.2020
    Mount Snow, USA

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  • Tampere Celiac Disease Symposium 2020

    18.09.2020 - 19.09.2020
    Tampere, Finland

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