Fibrin aggregation and clotting

Fibrinogen, purfied from human plasma

Quantity Unit Price Status
50 mg 250 € Available
Documents
Art. No.
F004
Synonym
Factor I
Background info
Fibrinogen (factor I) is a plasma glycoprotein that is converted by thrombin into fibrin during blood coagulation. Fibrin forms the blood clot and is subsequently cross linked by factor XIIIa. Human Factor I is a hexamer composed of three pairs of chains (α2β2γ2).
Molecular Weight
340 kDa
Source
Tested human plasma from healthy donors
Activation
Ca2+, Thrombin
Appearance
White solid
Solubility
20 mg/ml in water
Description
Fibrinogen (factor I) is a plasma glycoprotein that is converted by thrombin into fibrin during blood coagulation. Fibrin forms the blood clot and is subsequently cross linked by factor XIIIa. Human Factor I is a hexamer composed of three pairs of chains (α2β2γ2).
Storage
Store at 2 – 8 °C. DO NOT FREEZE! Stock solutions are reported to be stable for several hours. Delivery is possible at ambient temperature
Note
INTENDED FOR RESEARCH USE ONLY, NOT FOR USE IN HUMAN, THERAPEUTIC OR DIAGNOSTIC APPLICATIONS.

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