Background info
AndraconTM is a brand for high quality microbial transglutaminase:
• Recombinantly produced in E. coli
• Ultra-pure and highly active
• Batch to batch consistent quality
• License free
• Produced according to an SOP in an ISO9001:2015 certified environment
AndraconTM (Microbial Transglutaminase, MTG) catalyzes the acyl transfer reaction between γ-carboxyamide groups of peptide-bound glutamine residues and a variety or primary amines.
Therefore, AndraconTM can be used to attach primary-amine coupled functional markers like biotin, fluorescent dyes, click chemistry reagents or cytotoxins to proteins, e.g. antibodies.
Essentially, AndraconTM is used for the production of antibody drug conjugates (ADCs).
Application
Labeling, immobilisation, conjugation, and modification of proteins.
Reference(s)
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