Proteases

Art. No.

Z020

Synonym

Z-Gly-Gly-Arg-AMC

Molecular Formula

C30H34F3N7O9 (free base: C28H33N7O7)

Molecular Weight

693.63 (free base: 579.60)

Purity by HPLC

>95 % (214 nm)

Appearance

Pale yellow solid

Solubility

50 μM in 0.1% (v/v) DMSO / aqueous buffers Pre-dissolve e.g. 10 mg (14.4 μmol) in 288 μl DMSO - dilute e.g. 10 μl of that stock solution (50 mM) with 9,990 μl aqueous buffer to obtain a 50 μM solution. DMSO stock solutions can be stored at -20°C for at least 6 months. To avoid too many freeze thaw cycles, we strongly recommend storage of aliquots.

Application

“Slow” acting thrombin substrate for the determination of thrombin generation in plasma Also suitable for urokinase, trypsin, and tissue-type plasminogen

Storage

Store at -20°C, desiccate

Reference(s)

Kintigh J. et al. Res. Pract. Thromb. Haemost. 2017, 2, 42-48. Devreese K. et al. Thromb. Haemost. 2007, 98, 600-613. Hemker H.C. et al. Pathophysiol. Haemost. Thromb. 2002, 32, 249-253. Zimmerman M. et al. PNAS 1978, 75, 750-753.

Note

INTENDED FOR RESEARCH USE ONLY, NOT FOR USE IN HUMAN, THERAPEUTIC OR DIAGNOSTIC APPLICATIONS.

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